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KMID : 0368019870100010111
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Journal of Soonchunhyang University
1987 Volume.10 No. 1 p.111 ~ p.114
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CA 125 levels in pregnant Women
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차상헌/Cha, Sang Hun
유훈/이효표/Yoo, Hoon/Lee, Hyo Pyo
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Abstract
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To confirm the change in serum CA 125 levels in normal and abnormal pregnancy, we measured serum CA 125 levels in 86 normal pregnant women, 26 postpartum women and 16 abnormal pregnant women(14 of IUFD and 2 of H. mole), using an RIA kit. The mean CA 125 level(±S.D.) and positive rate(>35U/ml) for pregnant women at 4?11 weeks of gestation were 69.4±73.2U/ml and 70%, respectively, being the highest values in all the groups. On the contrary, those for pregnant women at 12-23 weeks of gestation were 26.9±10.1U/ml and 14.3%, respectively, the lowest in all gestational groups. Changes in serum CA 125 levels in normal pregnant women showed a decreasing trend with advance in gestation. The mean CA 125 level(±S.D:) for 14 patients with IUFD was 387.6±254.8U/ml and that for 2 patients with H. mole was 71.3+_14.1U/ml. Serum CA 125 levels in IUFD were higher than that in normal pregnancy. When we use CA 125 as a tumor marker for ovarian cancer, we must eliminate the factor of pregnancy. And it indicates that CA 125 can be used as an aid for the diagnosis of IUFD.
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KEYWORD
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